NeurosciencebioRxivPreprint
Divergent Molecular Pathways for Toxicity of Selected Mutant C9ORF72-derived Dipeptide Repeats
Sonia Okekenwa, Ming Ying Tsai, Patrick M. Dooley…·Yuyu Song
This study identifies compartment-specific toxic effects of C9ORF72-derived dipeptide repeats (DPRs) in neurodegenerative disease models, revealing two distinct pathogenic mechanisms contributing to ALS and FTD.
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