Author

Anne Nathalie Longakit

University of British ColumbiaORCID 0000-0002-5413-494XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Catherine D. Van RaamsdonkiD· 2 shared Hannah BourgetiD· 2 shared Alyssa YooiD· 1 shared Amy LutyiD· 1 shared Chloe HessiD· 1 shared Christina ZhangiD· 1 shared Oscar UrtatiziD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

Catherine D. Van RaamsdonkORCID

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2 papers

Recent·Most cited

Cancer BiologyCancer Research CommunicationsPeer-reviewedJan 13, 2025

Loss of neurofibromin accelerates uveal and dermal melanoma formation driven by GNAQ

Anne Nathalie Longakit, Oscar Urtatiz, Amy Luty…·Catherine D. Van Raamsdonk

This study shows that Nf1 loss accelerates melanoma formation in mice with GNAQ mutations, highlighting cAMP signaling and its link to MMNSTs.

5 citations

mousebulk RNA-seq

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GeneticsbioRxivPreprintJul 24, 2024

Mitf over-expression leads to microphthalmia and coloboma in Mitf-cre mice

Anne Nathalie Longakit, Hannah Bourget, Catherine D. Van Raamsdonk

The paper investigates the eye phenotype in Mitf-cre mice, finding that over-expression of Mitf-H and Mitf-D isoforms causes microphthalmia and coloboma due to transgene integration and altered gene expression.

DOI 10.1101/2024.07.24.605021

mouseexperimental assay

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