Author

Russell Ault

Children's Hospital of PhiladelphiaORCID 0000-0002-5430-5366Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1

Frequent Co-Authors

Amir MotmaeniD· 1 shared Armita NourmohammadiD· 1 shared Bingxu LiuiD· 1 shared Chunyu WangiD· 1 shared David A. BakeriD· 1 shared David A. ScheinbergiD· 1 shared Dionne K. VafeadosiD· 1 shared Gian Marco VisaniiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Amir MotmaenORCID

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1 paper

Recent·Most cited

Design of high specificity binders for peptide-MHC-I complexes

Bingxu Liu, Nathan F. Greenwood, Julia E. Bonzanini, Amir Motmaen, Jeremy Meyerberg, Tao Dao, Xinyu Xiang, Russell Ault, Jazmin Sharp, Chunyu Wang, Gian Marco Visani, Dionne K. Vafeados, Nicole Roullier, Armita Nourmohammad, David A. Scheinberg, , David A. Baker

The paper designs high specificity binders for peptide-MHC-I complexes using deep learning, achieving specific targeting of pMHCs and enabling T-cell activation.

Science · Jul 24, 2025Peer-reviewedImmunology