Drug repositioning for immunotherapy in breast cancer using single-cell and spatial transcriptomics analysis
Elyas Mohammadi, Han Jin, Cheng Zhang, Neda Shafizade, Samira Dashti, Simon Lam, Mojtaba Tahmoorespur, Adil Mardinoğlu, Mohammad Hadi Sekhavati
This study identifies immunomodulatory peptides deregulated in breast cancer using single-cell and spatial transcriptomics, and proposes drugs to modulate their expression.
medRxiv · Nov 18, 2022 · PreprintGenetic & Genomic Medicine