Role of CCK1 receptor in metabolic benefits of intestinal enteropeptidase inhibition in mice
Kamal A. Albarazanji, Simon A. Hinke, Cassandre Cavanaugh, Jianying Liu, Stephen Beck, Neetu Shukla, Rong Meng, George Ho, Raul C. Camacho, James N. Leonard, Andrea R. Nawrocki
This study investigates how CCK1 receptor signaling mediates the metabolic effects of enteropeptidase inhibition in mice, finding both CCK1R-dependent and -independent mechanisms contribute to weight loss.
PLoS ONE · Jun 3, 2025Peer-reviewedPharmacology & Toxicology