CellAwareGNN: Single-Cell Enhanced Knowledge Graph Foundation Model for Drug Indication Prediction
Xinmeng Zhang, Eugene Jeong, Chao Yan, Yubo Feng, Linshuoshuo Lyu, Xingyi Guo, You Chen
Adding OneK1K immune cell-type expression edges to an updated PrimeKG modestly improved drug-indication link prediction, AUPRC 0.816 to 0.826 overall and 0.847 to 0.864 for 40 autoimmune diseases.
ACM SIGKDD Conference on Knowledge Discovery and Data Mining (KDD) · Aug 6, 2026Peer-reviewedBioinformatics✦ In-depth digest