Controllable multi-halogenation of a non-native substrate by SyrB2 iron halogenase
R. Hunter Wilson, Sourav Chatterjee, Elizabeth R. Smithwick, Anoop Rama Damodaran, Ambika Bhagi‐Damodaran
This paper demonstrates how SyrB2 iron halogenase can controllably halogenate non-native substrates to produce mono-, di-, and tri-chlorinated products by adjusting cofactor loading and electron transfer.
ACS Catalysis · Aug 19, 2024Peer-reviewedBiochemistry