Author

Shinji Hirotsune

Osaka City UniversityORCID 0000-0002-5451-087XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

Fiona FrancisiD· 1 shared Kanako Kumamoto· 1 shared Makoto SatoiD· 1 shared Maxime Penisson· 1 shared Mingyue JiniD· 1 shared Richard BelvindrahiD· 1 shared Ryuichi IshidaiD· 1 shared Shengming Wang· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

Fiona FrancisORCID

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2 papers

Recent·Most cited

Lis1 mutation prevents basal radial glia-like cell production in the mouse

Maxime Penisson, Mingyue Jin, Shengming Wang, Shinji Hirotsune, Fiona Francis, Richard Belvindrah

The paper investigates the role of Lis1 in generating basal radial glia-like cells in the mouse, showing that Lis1 depletion prevents their formation and disrupts brain development.

Human Molecular Genetics · Oct 7, 2021Peer-reviewedNeuroscience

Developmental Downregulation of LIS1 Expression Limits Axonal Extension and Allows Axon Pruning

Kanako Kumamoto, Tokuichi Iguchi, Ryuichi Ishida, Takuya Uemura, Makoto Sato, Shinji Hirotsune

This study shows that developmental downregulation of LIS1 limits axonal extension and allows axon pruning, which is essential for neuronal circuit formation but hinders nerve regeneration.

Biology Open · Jan 1, 2017Peer-reviewedNeuroscience