Substrate-engaged type III secretion system structures reveal gating mechanism for unfolded protein translocation
Sean Miletic, Dirk Fahrenkamp, Nikolaus Goessweiner‐Mohr, Jiri Wald, Maurice Pantel, Oliver Vesper, Vadim Kotov, Thomas C. Marlovits
The paper reports the structure of an active Salmonella T3SS needle complex engaged with SptP, revealing the mechanism of unfolded protein translocation through the secretion conduit.
Nature Communications · Mar 9, 2021Peer-reviewedMolecular Biology