GenomicsCell ReportsPeer-reviewed
Truncated RNA-binding protein production by DUX4-induced systemic inhibition of nonsense-mediated RNA decay
Amy E. Campbell, Michael C. Dyle, Roberto Albanese…·Sujatha Jagannathan
The paper shows that inhibiting NMD in FSHD leads to widespread production of truncated RNA-binding proteins, some of which are toxic and can be detected in patient samples.
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