Author

Roshan Nepal

Basil Hetzel InstituteORCID 0000-0002-5469-3397Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Abdul Rehaman· 1 shared Alkis James PsaltisiD· 1 shared Bijita NeupaneiD· 1 shared Binod Khadka· 1 shared David Pun· 1 shared Dipendra Kumar MandaliD· 1 shared Elisha Upadhyaya· 1 shared Gaurav AdhikariiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMicrobiology

Abdul Rehaman

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2 papers

Recent·Most cited

Mutations in mfd cause Staphylococcus aureus mucoid hyper-biofilm phenotype in chronic rhinosinusitis

Ghais Houtak, Ian R. Monk, Muhammed Awad, Roshan Nepal, Mahnaz Ramezanpour, Alkis James Psaltis, Peter‐John Wormald, George Spyro Bouras, Timothy Paul Stinear, Sarah Vreugde

The paper identifies mutations in the mfd gene in S. aureus isolates from a CRS patient, linking them to a mucoid hyper-biofilm phenotype and increased enterotoxin production.

bioRxiv · Jul 2, 2026 · PreprintMicrobiology

Harnessing Lytic Phages for Biofilm Control in Carbapenem-Resistant Klebsiella pneumoniae Causing Urinary Tract Infection

Dipendra Kumar Mandal, Elisha Upadhyaya, Puja Dahal, Gaurav Adhikari, Rojina Pandey, Abdul Rehaman, Sudip Timilsina, Pragya Sapkota, Shobha Amagain, David Pun, Kundan Khadka, Keshab Gorathoki, Bijita Neupane, Sangharsika Chaudhary, Sushila Thapa, , Rajani Malla

This study isolates and characterizes a lytic phage effective against carbapenem-resistant Klebsiella pneumoniae, showing strong biofilm disruption and stability.

Microbiology Spectrum · May 29, 2026Peer-reviewedMicrobiology