Rafael Jaimes

This study computationally models H5 influenza variants against HA1-neutralizing antibodies, showing weakening antibody binding over time and increased immune evasion risks.

This paper provides a comprehensive guide for quality control metrics and mitigation strategies for 11 epigenetics and transcriptomics assays to improve exposure signature discovery.

The paper uses virtual screens to predict cytokine-nucleocapsid protein interactions across coronaviruses, comparing AlphaFold2-Multimer and HADDOCK, and introduces a new algorithm for assessing binding interfaces.

This paper uses a Bayesian language model to design high-affinity scFv antibody libraries, achieving 28.8-fold better binding than directed evolution.