Cancer BiologyCancer Immunology ResearchPeer-reviewed
Effects of clinically relevant radionuclides on the activation of a type I interferon response by radiopharmaceuticals in syngeneic murine tumor models
Caroline P. Kerr, Julia Sheehan‐Klenk, Joseph J. Grudzinski…·Zachary Scott Morris
This study examines how different radionuclides affect the type I interferon response in tumor models and shows that 225Ac enhances immunotherapy response via STING-dependent mechanisms.
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