Author

Sven Halbedel

Robert Koch InstituteORCID 0000-0002-5575-8973Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 2 Assay:whole-genome sequencing· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Sabrina WampiD· 3 shared Alexander KrüttgeniD· 1 shared Antje FliegeriD· 1 shared Dunja BruderiD· 1 shared Franziska SchuleriD· 1 shared Gudrun HollandiD· 1 shared Janina Döhling· 1 shared Jeanine RismondoiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersMicrobiology

Sabrina WampORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

On the role of cell chaining in the attenuation of a Listeria monocytogenes divIVA mutant

Sabrina Wamp, Gudrun Holland, Jeanine Rismondo, Sven Halbedel

This study investigates how cell chaining in a Listeria monocytogenes divIVA mutant affects virulence, finding that it is not the morphology itself but PrfA- and SecA2-dependent processes that are primarily responsible for attenuation.

Virulence · Aug 9, 2026Peer-reviewedMicrobiology

Three metabolic pathways replenishing the one-carbon pool collectively support growth and virulence of Listeria monocytogenes

Sandra Freier, Sarah Frentzel, Moritz Müller, Susan Scheffler, Sabrina Wamp, Tim Engelgeh, Janina Döhling, Dunja Bruder, Sascha Kahlfuß, Sven Halbedel

This study identifies three metabolic pathways that replenish the one-carbon pool in Listeria monocytogenes, supporting its growth and virulence.

bioRxiv · Sep 10, 2025 · PreprintMicrobiology

A pbpB1 mutation causing β-lactam resistance in clinical Listeria monocytogenes isolates

Sabrina Wamp, Rosalyn Wagner, Franziska Schuler, Alexander Krüttgen, Antje Flieger, Sven Halbedel

This study identifies a pbpB1 mutation causing β-lactam resistance in Listeria monocytogenes isolates and shows its selection during antibiotic treatment.

bioRxiv · Apr 22, 2025 · PreprintMicrobiology