The paper identifies HERC4 as a regulator of ROS-induced DNA damage during bacterial and viral-bacterial infections, showing its role in DNA repair and potential as a therapeutic target.

DOI 10.64898/2026.07.02.736007

humanmouse

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MicrobiologybioRxivPreprintSep 10, 2025

Three metabolic pathways replenishing the one-carbon pool collectively support growth and virulence of Listeria monocytogenes

Sandra Freier, Sarah Frentzel, Moritz Müller…·Sven Halbedel

This study identifies three metabolic pathways that replenish the one-carbon pool in Listeria monocytogenes, supporting its growth and virulence.

2 citations

bacteria (other)DNA methylation

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Molecular BiologyScientific ReportsPeer-reviewedNov 28, 2023

Generation of OP7 chimera defective interfering particle preparations free of infectious influenza A virus that shows antiviral efficacy in mice

Tanya Dogra, Lars Pelz, Julia Désirée Boehme…·Udo Reichl

10 citations

mouseexperimental assay

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Synthetic BiologyFrontiers in Bioengineering and BiotechnologyPeer-reviewedAug 16, 2021

Cell-free glycoengineering of the recombinant SARS-CoV-2 spike glycoprotein

Johannes Ruhnau, Valerian Grote, Mariana Juarez-Osorio…·Udo Reichl

The paper describes an in-vitro glycoengineering approach to modify N-glycans on recombinant SARS-CoV-2 spike glycoprotein to mimic mammalian cell-derived glycoforms.

10 citations

protein structureexperimental assay

𝕏 PostBluesky