Structural analyses of apolipoprotein A-IV polymorphisms Q360H and T347S elucidate the inhibitory effect against thrombosis
Aron A. Shoara, Sladjana Slavkovic, Miguel A. D. Neves, Preeti Bhoria, Viktor Prifti, Pingguo Chen, Logan W. Donaldson, Andrew Beckett, Philip E. Johnson, Heyu Ni
This study examines how apoA-IV polymorphisms Q360H and T347S affect its structure and function, revealing reduced inhibitory effects against thrombosis and potential links to cardiovascular disease.
Journal of Biological Chemistry · Mar 10, 2025Peer-reviewedBiochemistry