Author

Philip E. Johnson

York UniversityORCID 0000-0002-5573-4891Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Assay:DNA methylation· 2 Research Focus:protein structure prediction· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Cameron D. MackerethiD· 2 shared Eric LargyiD· 2 shared Andrew BeckettiD· 1 shared Andriy KryshtafovychiD· 1 shared Anna LewickaiD· 1 shared Anna‐Lena SteckelbergiD· 1 shared Aron A. ShoaraiD· 1 shared Brune VialetiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

Cameron D. MackerethORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Unconventional DNA architecture in a dopamine-bound aptamer complex

Emily Hoi Pui Chao, Eric Largy, Yunus A. Kaiyum, Minh‐Dat Nguyen, Brune Vialet, Philippe Dauphin‐Ducharme, Philip E. Johnson, Cameron D. Mackereth

This study determines the structure of a dopamine-binding DNA aptamer using NMR, revealing an unconventional DNA fold distinct from typical DNA structures and providing insights into its specificity and potential applications in biosensor design.

bioRxiv · Nov 27, 2025 · PreprintBiochemistry

Functional relevance of CASP16 nucleic acid predictions as evaluated by structure providers

Rachael C. Kretsch, Reinhard Albrecht, Ebbe Sloth Andersen, Hsuan‐Ai Chen, Wah Chiu, Rhiju Das, Jeanine Gezelle, Marcus D. Hartmann, Claudia Höbartner, Yimin Hu, Shekhar Jadhav, Philip E. Johnson, Christopher P. Jones, Deepak Koirala, Emil L. Kristoffersen, , Andriy Kryshtafovych

Structure providers for 18 CASP16 nucleic acid targets find blind predictions capture secondary structure but miss non-canonical interactions, backbone kinks, ligand sites, and intermolecular interfaces.

Proteins Structure Function and Bioinformatics · Sep 4, 2025Peer-reviewedBiophysics✦ In-depth digest

Structural analyses of apolipoprotein A-IV polymorphisms Q360H and T347S elucidate the inhibitory effect against thrombosis

Aron A. Shoara, Sladjana Slavkovic, Miguel A. D. Neves, Preeti Bhoria, Viktor Prifti, Pingguo Chen, Logan W. Donaldson, Andrew Beckett, Philip E. Johnson, Heyu Ni

This study examines how apoA-IV polymorphisms Q360H and T347S affect its structure and function, revealing reduced inhibitory effects against thrombosis and potential links to cardiovascular disease.

Journal of Biological Chemistry · Mar 10, 2025Peer-reviewedBiochemistry