Nader Sanai

This paper evaluates the combination of HDAC and ATM inhibition with radiation in glioblastoma models, finding synergistic radiosensitization in vitro but no additional survival benefit in vivo.

This study identifies genetic changes in IDH-mutant gliomas that correlate with treatment response and tumor evolution using longitudinal genomic data from 206 patient samples.

This paper introduces a method to enhance antibody penetration in thick tissues using pressurized immunohistochemistry, improving staining uniformity, intensity, and depth while reducing staining time for thin sections.

The paper uses single-cell and single-nucleus sequencing to analyze glioblastoma microenvironment composition and interactions, identifying diverse cell types and pathway rewiring.