Author

Thi Thuy Nguyen

Hong Kong University of Science and TechnologyORCID 0000-0002-5584-1013Unclaimed ORCID profile · follow to get notified of new preprints

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Thi Thuy Nguyen1 paper · Hong Kong University of Science and Technology

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:structural biology· 1

Frequent Co-Authors

Dongbo DingiD· 1 shared Matthew Yu Hin PangiD· 1 shared Mingxi DengiD· 1 shared Tingyu Jin· 1 shared Toyotaka IshibashiiD· 1 shared Xinpeng Bai· 1 shared Yan YaniD· 1 shared Yingyi ZhangiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Dongbo DingORCID

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1 paper

Recent·Most cited

H2B.W2, a Spermatocytes-specific Histone Variant, disrupts nucleosome stability and reduces chromatin compaction

Thi Thuy Nguyen, Dongbo Ding, Xinpeng Bai, Matthew Yu Hin Pang, Mingxi Deng, Yue Liu, Tingyu Jin, Zhichun Xu, Yingyi Zhang, Yuanliang Zhai, Yan Yan, Toyotaka Ishibashi

This study identifies H2B.W2 as a spermatocyte-specific histone variant that destabilizes nucleosomes and reduces chromatin compaction, potentially regulating gene expression during spermatogenesis.

Nucleic Acids Research · Aug 27, 2025Peer-reviewedBiochemistry