The Landscape of Sex- and APOE Genotype-Specific Transcriptional Changes in Alzheimer's Disease at the Single Cell Level
Gongqi Yu, Abigail L. Thorpe, Qi Zeng, Erming Wang, Dongming Cai, Minghui Wang, Bin Zhang
This study investigates sex and APOE genotype-specific transcriptional changes in Alzheimer's disease using single-cell transcriptomics, identifying cell-type-specific differences across 54 high-resolution cell types.
bioRxiv · Dec 1, 2024 · PreprintGenomics