Author

Luming Yin

Emory University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 6 Systems Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 9 Assay:proteomics· 8 Approach:statistical model· 7 Research Focus:differential expression· 5 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:database / resource· 2 Approach:experimental assay· 2

Frequent Co-Authors

Nicholas T. SeyfriediD· 9 shared Allan I. LeveyiD· 8 shared James J. LahiD· 8 shared Eric B. DammeriD· 7 shared Lingyan PingiD· 6 shared David Alan BennettiD· 5 shared Marla GearingiD· 5 shared Philip L. De JageriD· 5 shared

Activity by Year

2020-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

9 shared papersNeuroscience

Nicholas T. SeyfriedORCID

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Temporal RNA splicing dysregulation in a human multicellular model of C9orf72 ALS

Berna Aliya, Shiqi Liu, Alison Mansfield, Solan Xiyuan Yao, Sabra Mouhi, Supriya S. Wariyar, Jesse Seth Tenkorang, Nuri E. Smith, Mingee Chung, Ah Joung Rachel Yu, Taylor Pio, Najah E.J. Smith, Sabrina H. Zhu, Adam N. Trautwig, Janani Parameswaran, , Jimena Andersen

This study uses human spinal cord organoids to model C9orf72 ALS, identifying early RNA splicing dysregulation and RBP network dysfunction as key features of the disease.

bioRxiv · Oct 14, 2026 · PreprintNeuroscience

Large- Scale Deep Proteomic Analysis in Alzheimer's Disease Brain Regions Across Race and Ethnicity

Fatemeh Seifar, Edward J. Fox, Anantharaman Shantaraman, Yue Liu, Eric B. Dammer, Erica S. Modeste, Duc M. Duong, Luming Yin, Adam N. Trautwig, Qi Jin Guo, Kaiming Xu, Lingyan Ping, Joseph S. Reddy, Mariet Allen, Zachary Quicksall, , Nicholas T. Seyfried

The paper performs large-scale proteomic analysis of Alzheimer's disease brain regions across different racial and ethnic groups, identifying AD-related protein changes and APOE4 concordance with genotype.

Alzheimer s & Dementia · Nov 13, 2024Peer-reviewedNeuroscience

Bridging the Gap: Multi-Omics Profiling of Brain Tissue in Alzheimer's Disease and Older Controls in Multi-Ethnic Populations

Joseph S. Reddy, Laura M. Heath, Abby Vander Linden, Mariet Allen, Kátia de Paiva Lopes, Fatemeh Seifar, Erming Wang, Yiyi Ma, William L. Poehlman, Zachary Quicksall, Alexi M. Runnels, Yanling Wang, Duc M. Duong, Luming Yin, Kaiming Xu, , Nilüfer Ertekin‐Taner

This paper presents a multi-omics dataset from multi-ethnic Alzheimer's disease brain donors, including transcriptome, genome, and proteome data, to improve precision medicine for underrepresented populations.

Alzheimer s & Dementia · Aug 30, 2024Peer-reviewedNeuroscience

Network Proteomics of the Lewy Body Dementia Brain Reveals Presynaptic Signatures Distinct from Alzheimer's Disease

Anantharaman Shantaraman, Eric B. Dammer, Obiadada Ugochukwu, Duc Minh Duong, Luming Yin, E. Kathleen Carter, Marla Gearing, Alice S. Chen‐Plotkin, Edward B. Lee, John Q. Trojanowski, David Alan Bennett, James J. Lah, Allan I. Levey, Nicholas T. Seyfried, Lenora A. Higginbotham

This study identifies distinct presynaptic protein networks in Lewy body dementia that differ from Alzheimer's disease using network proteomics.

Molecular Neurodegeneration · Aug 6, 2024Peer-reviewedSystems Biology

Global analysis of the heparin-enriched plasma proteome captures matrisome-associated proteins in Alzheimer's disease

Qi Jin Guo, Lingyan Ping, Eric B. Dammer, Duc Minh Duong, Luming Yin, Kaiming Xu, Anantharaman Shantaraman, Edward J. Fox, Erik C. B. Johnson, Blaine Russell Roberts, James J. Lah, Allan I. Levey, Nicholas T. Seyfried

The paper uses heparin affinity chromatography to enrich plasma proteomes in Alzheimer's disease, identifying matrisome-associated proteins correlated with AD biomarkers.

bioRxiv · Nov 6, 2023 · PreprintNeuroscience

Unbiased Classification of the Human Brain Proteome Resolves Distinct Clinical and Pathophysiological Subtypes of Cognitive Impairment

Lenora A. Higginbotham, Kathleen Carter, Eric B. Dammer, Rafi U. Haque, Erik C. B. Johnson, Duc M. Duong, Luming Yin, Philip L. De Jager, David Alan Bennett, James J. Lah, Allan I. Levey, Nicholas T. Seyfried

The paper uses proteomic profiling to classify cognitive impairment subtypes in human brain tissues, identifying distinct molecular patterns associated with different clinical outcomes.

bioRxiv · Jul 22, 2022 · PreprintNeuroscience

Large-Scale Deep Multi-Layer Analysis of Alzheimer's Disease Brain Reveals Strong Proteomic Disease-Related Changes Not Observed at the RNA Level

Erik C. B. Johnson, Kathleen Carter, Eric B. Dammer, Duc M. Duong, Ekaterina Sergeevna Gerasimov, Yue Liu, Jiaqi Liu, Ranjita S. Betarbet, Lingyan Ping, Luming Yin, Geidy E. Serrano, Thomas G. Beach, Junmin Peng, Philip L. De Jager, Vahram H. Haroutunian, , Nicholas T. Seyfried

The paper analyzes proteomic data from Alzheimer's disease brains, revealing disease-related changes not seen at the RNA level and identifying potential therapeutic targets.

Nature Neuroscience · Feb 1, 2022Peer-reviewedSystems Biology

Global quantitative analysis of the human brain proteome and phosphoproteome in Alzheimer's disease

Lingyan Ping, Sean R. Kundinger, Duc Minh Duong, Luming Yin, Marla Gearing, James J. Lah, Allan I. Levey, Nicholas T. Seyfried

The paper quantitatively analyzes the human brain proteome and phosphoproteome in Alzheimer's disease across different stages using TMT labeling and mass spectrometry.

Scientific Data · Sep 28, 2020Peer-reviewedNeuroscience

A Consensus Proteomic Analysis of Alzheimer's Disease Brain and Cerebrospinal Fluid Reveals Early Changes in Energy Metabolism Associated with Microglia and Astrocyte Activation

Erik C. B. Johnson, Eric B. Dammer, Duc Minh Duong, Lingyan Ping, Maotian Zhou, Luming Yin, Lenora A. Higginbotham, Andrew Guajardo, Bartholomew White, Juan Carlos Troncoso, Madhav Thambisetty, Thomas Jude Montine, Edward B. Lee, John Q. Trojanowski, Thomas G. Beach, , Nicholas T. Seyfried

The paper identifies protein network modules in Alzheimer's disease brains and cerebrospinal fluid that are associated with energy metabolism and neuroinflammation, suggesting potential biomarkers and therapeutic targets.

Nature Medicine · Apr 13, 2020Peer-reviewedSystems Biology