Erming Wang

The paper develops a multi-omics cohort of prefrontal cortex data from cognitively normal older adults to identify molecular signatures of cognitive resilience to Alzheimer's disease.

This study investigates sex and APOE genotype-specific transcriptional changes in Alzheimer's disease using single-cell transcriptomics, identifying cell-type-specific differences across 54 high-resolution cell types.

The paper performs large-scale proteomic analysis of Alzheimer's disease brain regions across different racial and ethnic groups, identifying AD-related protein changes and APOE4 concordance with genotype.

This paper presents a multi-omics dataset from multi-ethnic Alzheimer's disease brain donors, including transcriptome, genome, and proteome data, to improve precision medicine for underrepresented populations.

The paper identifies an AD-like subtype in brain aging across multiple regions, showing overlap with AD gene signatures and regional differences in gene expression.

This study uses proteomic profiling of intracranial atherosclerotic plaques to identify differentially expressed proteins associated with ICAD, revealing potential biomarkers and biological pathways involved in the disease.

This study investigates the proteomic and phosphoproteomic effects of DUSP4 overexpression in 5xFAD mice, revealing sex-specific molecular mechanisms and validating findings in human AD cohorts.

This study identifies molecular networks and key regulators in Alzheimer’s Disease using integrative genomics and experimental validation.