Author

Jeanne Lainé

Inserm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 2 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Gilles MoulayiD· 2 shared Mai Thao BuiiD· 2 shared Marc BitouniD· 2 shared Norma Beatriz RomeroiD· 2 shared Sofia Benkhelifa‐ZiyyatiD· 2 shared Stéphane VassilopoulosiD· 2 shared Vincent MoulyiD· 2 shared Agathe FranckiD· 1 shared

Activity by Year

2018-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMolecular Biology

Gilles MoulayORCID

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Author profile →

4 papers

Recent·Most cited

Early endosome disturbance and endolysosomal pathway dysfunction in Duchenne muscular dystrophy

Julie Chassagne, Nathalie Da Silva, Ines Akrouf, Bruno Cadot, Laura Julien, Inès Barthélémy, Stéphane Blot, Caroline Le Guiner, Mai Thao Bui, Norma Beatriz Romero, Jeanne Lainé, France Piétri‐Rouxel, Pierre Meunier, Kamel Mamchaoui, Stéphanie Lorain, , Sofia Benkhelifa‐Ziyyat

This study identifies endosomal pathway dysfunction in DMD muscle cells and shows that Rab5 upregulation contributes to endosomal defects, which can be mitigated by Rab5 knock-down or dystrophin restoration.

American Journal Of Pathology · Jun 9, 2025Peer-reviewedPathology

Alternative splicing of SORBS1 affects neuromuscular junction formation and stability in myotonic dystrophy type 1

Caroline Hermitte, Hortense de Calbiac, Gilles Moulay, Antoine Mérien, Jeanne Lainé, Hélène Polvèche, Michel Cailleret, Stéphane Vassilopoulos, Edor Kabashi, Denis Furling, Cécile Martinat, Morgan Gazzola

This study shows that abnormal splicing of SORBS1 exon 25 in DM1 contributes to neuromuscular junction formation and stability issues in skeletal muscle.

bioRxiv · Dec 23, 2024 · PreprintMolecular Biology

Guanabenz treatment improves Oculopharyngeal muscular dystrophy phenotype

Alberto Malerba, Fanny Roth, Pradeep Harish, Jamila Dhiab, Ngoc Lu-Nguyen, Ornella Cappellari, Susan Jarmin, Alexandrine Mahoudeau, Victor Ythier, Jeanne Lainé, Elisa Negroni, Emmanuelle Abgueguen, Martine Simonelig, Philippe Guedat, Vincent Mouly, , Capucine Trollet

This study shows that guanabenz acetate reduces PABPN1 aggregates and improves muscle function in an OPMD mouse model by modulating the UPR.

bioRxiv · Jul 24, 2018 · PreprintPathology

Mechanosensitive clathrin platforms anchor desmin intermediate filaments in skeletal muscle

Agathe Franck, Jeanne Lainé, Gilles Moulay, Michaël Trichet, Christel Gentil, Anaïs Fongy, Anne Bigot, Sofia Benkhelifa-Ziyyat, Emmanuelle Lacène, Mai Thao Bui, Guy Brochier, Pascale Guicheney, Sabrina Sacconi, Vincent Mouly, Norma Romero, , Stéphane Vassilopoulos

This study shows that clathrin plaques and dynamin 2 anchor desmin intermediate filaments and regulate YAP signaling in skeletal muscle in response to mechanical cues.

bioRxiv · Jul 18, 2018 · PreprintCell Biology