Francesca Mandino

The paper uses Bayesian generative modeling to show the mouse brain's functional connectome has multiple co-dominant organizational configurations rather than a single structure.

The paper investigates the neural origins of quasi-periodic patterns in resting-state fMRI using combined calcium imaging and fMRI, finding a time-locked correlation between neural activity and BOLD signals.

The paper introduces channel capacity as a measure of directed information transfer between brain regions and validates it across human and rodent neuroimaging datasets to assess its sensitivity, specificity, and temporal variability.

This paper introduces a biphasic acclimation protocol for simultaneous wide-field fluorescent Ca2+ imaging and fMRI in awake mice, showing convergent and divergent patterns in brain function between modalities.

The paper uses simultaneous calcium imaging and fMRI in mice to identify cell-type specific signals in the brain with high spatiotemporal resolution.

This paper develops a geometrically constrained framework to map brain regions across species and shows geometry influences regional organization through patterning molecules.

This study uses dynamic functional connectivity to identify brain states related to behavior and traits, finding that aggregated data across scans performs better than isolated time points for trait prediction.

This study investigates the effects of repetitive mild closed-head injury on synaptic density and BOLD-fMRI signal homogeneity in mice, finding decreased synapse density and increased regional homogeneity.

The paper uses Ca2+ imaging and fMRI-BOLD in mice to compare functional network organization, finding overlapping but distinct patterns between modalities.

The paper uses fMRI to track functional connectivity changes in a mouse model of Alzheimer's disease over time and shows that mGluR5 modulator treatment reverses these deficits.

This study shows PTEN mutations cause ventriculomegaly and cortical network dysfunction through neural precursor and interneuron dysregulation, with mTORC1 inhibition offering therapeutic potential.

The paper introduces a pipeline for analyzing widefield calcium imaging data and shows how functional network properties differ with wakefulness and across cell types.

StandardRat improves functional connectivity specificity in rat brains through a standardized MRI protocol tested across 20 centers.

The paper shows how theta frequency modulation enables selective information routing in brain networks, which is impaired in Alzheimer's disease models.

The paper identifies functional connectivity gradients in the mouse cortex that align with neocortical evolution and sensory specialization across multiple datasets.

This study identifies a dichotomic hypo-connected resting and hyper-responsive active phenotype in a mouse model of early tauopathy, with implications for Alzheimer's disease.

This study identifies reproducible resting-state networks in the mouse brain across multiple centers using standardized rsfMRI analysis.