Pharmacology & ToxicologybioRxivPreprint
G protein-coupled receptor 35 (GPR35) stimulation reduces osteoclast activity in primary human bone cells
Maria L. Price, Rachael A. Wyatt, Ana Crastin…·Caroline M. Gorvin
This study shows GPR35 agonists reduce osteoclast activity in human cells by inhibiting bone resorption pathways, with effects comparable to existing osteoporosis drugs.
DOI 10.1101/2025.04.21.649743