Blanca I. Aldana

This study shows that mitochondrial pyruvate import in astrocytes is essential for maintaining neurotransmitter homeostasis and seizure resistance, rather than primarily for bioenergetic purposes.

This paper shows that loss of IFNAR1 in neurons and astrocytes disrupts brain energy metabolism and leads to Parkinsonian dementia-like features in mice.

This study investigates microglial metabolism and its impact on neuronal metabolism using isotope tracing and GC-MS, revealing novel metabolic functions and interactions.

This paper demonstrates that pretargeted PET imaging of CNS targets using monoclonal antibodies is feasible, achieving specific binding to Aβ-bound antibodies.

The paper assesses metabolic and oxidative stress in NTG by analyzing skin fibroblasts, finding no significant differences compared to controls.

This study shows that palmitate exposure causes microglia to change their metabolism and release EVs that affect behavior and metabolism in mice.

The paper identifies Golgi fragmentation as an early AD phenotype in neurons using stem cell and mouse models, showing its link to SORL1 variants and glycosylation changes.