NeurosciencebioRxivPreprint
Reduced progranulin increases tau and alpha-synuclein inclusions and alters phenotypes of tauopathy mice via glucocerebrosidase
Hideyuki Takahashi, Sanaea Z. Bhagwagar, Sarah Helena Nies…·Stephen M. Strittmatter
This study shows that reduced progranulin increases tau and alpha-synuclein inclusions and worsens tauopathy mouse phenotypes via glucocerebrosidase.
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