CryoEM structure of ALK2:BMP6 reveals distinct mechanisms that allow ALK2 to interact with both BMP and Activin ligands
Erich J. Goebel, Senem Aykul, Warren W. Hom, Kei Saotome, Aris N. Economides, Matthew C. Franklin, Vincent J. Idone
This paper presents the cryoEM structure of ALK2:BMP6, revealing distinct mechanisms for ALK2's interaction with BMP and activin ligands.
Proceedings of the National Academy of Sciences · Aug 25, 2025Peer-reviewedBiochemistry