Author

Warren W. Hom

Regeneron (United States)ORCID 0000-0003-0521-596XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Organism:human· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Aris N. EconomidesiD· 2 shared Erich J. GoebeliD· 2 shared Senem AykuliD· 2 shared Vincent J. IdoneiD· 2 shared John B. Lees‐ShepardiD· 1 shared Kaitlin N. LydoniD· 1 shared Kei SaotomeiD· 1 shared Krunal PateliD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiochemistry

Aris N. EconomidesORCID

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2 papers

Recent·Most cited

BiochemistryProceedings of the National Academy of SciencesPeer-reviewedAug 25, 2025

CryoEM structure of ALK2:BMP6 reveals distinct mechanisms that allow ALK2 to interact with both BMP and Activin ligands

Erich J. Goebel, Senem Aykul, Warren W. Hom…·Vincent J. Idone

This paper presents the cryoEM structure of ALK2:BMP6, revealing distinct mechanisms for ALK2's interaction with BMP and activin ligands.

2 citations

cryo-EMexperimental assay

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Cell BiologybioRxivPreprintJan 29, 2024

Coordinate regulation of Activin and Bone Morphogenetic Protein signaling by a lysosomal trafficking switch

Warren W. Hom, Senem Aykul, Lampros Panagis…·Aris N. Economides

The paper shows that ActA forms non-signaling complexes with ACVR1 that are trafficked to lysosomes and degraded, unlike Activin B, AC, and AB which remain on the surface.

1 citation

humanexperimental assay

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