NeurosciencebioRxivPreprint
Early disruption of entorhinal dopamine in a knock-in model of Alzheimer's disease
Tatsuki Nakagawa, Jiayun L. Xie, Marjan Savadkohighodjanaki…·Kei M. Igarashi
This study identifies early dysfunction of LEC-projecting dopamine neurons in AD mice, linking it to memory impairments and suggesting therapeutic potential through optogenetics or L-DOPA.
DOI 10.1101/2024.10.10.617678