Molecular BiologyThe EMBO JournalPeer-reviewed
An alternative UPF1 isoform drives conditional remodeling of nonsense-mediated mRNA decay
Sarah E. Fritz, Soumya Ranganathan, Clara D. Wang, J. Robert Hogg
This study identifies an alternative UPF1 isoform, UPF1LL, that enables condition-dependent remodeling of NMD specificity by overcoming RNA binding proteins to target long 3UTRs and respond to stress.
36 citations