Author
National Institutes of HealthORCID 0000-0002-7522-1719Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Emily A. Dangelmaier, Dorthy Fang, Isabel Hardy…·Sigrid Nachtergaele
This study shows that m6A methylation stabilizes genes involved in temozolomide resistance in glioblastoma, and inhibiting METTL3 can restore drug sensitivity.
Joseph H. Chapman, Jonathan M. Craig, Clara D. Wang…·J. Robert Hogg
The paper identifies UPF1 mutants with impaired helicase activity but intact ATPase activity that still support efficient nonsense-mediated mRNA decay in human cells.
Sarah E. Fritz, Soumya Ranganathan, Clara D. Wang, J. Robert Hogg
This study identifies an alternative UPF1 isoform, UPF1LL, that enables condition-dependent remodeling of NMD specificity by overcoming RNA binding proteins to target long 3UTRs and respond to stress.