BiochemistrybioRxivPreprint
Exploring T. cruzi IMPDH as a promising target through Chagas Box screening and AVN-944 inhibition
Ángel Lobo-Rojas, Letícia Marchese, Amanda Gonçalves Eufrásio…·Artur T. Cordeiro
The paper identifies TcIMPDH as a druggable target for Chagas disease and shows AVN-944 has potent inhibition and selectivity in infected cells.
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