Author

Hedden Ranfley

Universidade de São PauloORCID 0000-0002-5683-4173Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:benchmark study· 1 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Niels Olsen Saraiva CâmaraiD· 2 shared Anthony Gabry da SilveiraiD· 1 shared Ari WaismaniD· 1 shared Beatriz Leocata· 1 shared Bruno Junior NevesiD· 1 shared Camila Pontes FerreiraiD· 1 shared Carlos Frederico Martins MenckiD· 1 shared Cristiane Naffah de Souza BredaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

Niels Olsen Saraiva CâmaraORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Th17 cells require the DNA repair sensor XPC to control oxidative DNA damage

Jefferson Antônio Leite, Natalia Notarberardino Bos, Luísa Menezes-Silva, Eloísa Martins da Silva, Giovana da Silva Leandro, Guilherme Comparotto Moreira de Goes, Patrick da Silva, S. A. Oliveira, Eder Soares de Almeida Santos, Hedden Ranfley, Ilaria Palagi, Magaiver Andrade-Silva, Camila Pontes Ferreira, José Arimatéa de Oliveira Nery Neto, Victor Yuji Yariwake, , Niels Olsen Saraiva Câmara

This study identifies XPC as essential for protecting Th17 cells from oxidative DNA damage, showing its role in DNA repair, differentiation, and function.

Nature Communications · Apr 1, 2026Peer-reviewedImmunology

NLRP1 Shapes Immune and Inflammatory Signatures in Human Melanoma but Not in Mouse Models

Vitor Pedro Targhetta, Raquel de Souza Vieira, Hedden Ranfley, Cristiane Naffah de Souza Breda, Niels Olsen Saraiva Câmara

This study shows NLRP1 improves prognosis in human melanoma but not in mouse models, and highlights its potential as a prognostic biomarker and therapeutic target.

bioRxiv · Nov 24, 2025 · PreprintImmunology