Author

Patrick da Silva

Brigham and Women's HospitalORCID 0000-0002-3481-4972Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Patrick da Silva1 paper · Harvard University

Biology Disciplines

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Immunology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Howard L. WeineriD· 2 shared Saef IzzyiD· 2 shared Akiko IwasakiiD· 1 shared Amir Alawi· 1 shared Anthony Gabry da SilveiraiD· 1 shared Ari WaismaniD· 1 shared Aryan Rajput· 1 shared Beatriz Leocata· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersImmunology

Howard L. WeinerORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

NeurosciencebioRxivPreprintSep 11, 2026

Brain-resident myeloid cells promote rapid leukocyte adhesion in leptomeningeal vessels after anti-Aβ immunotherapy

Moustafa Algamal, Shinya Yokomizo, Wadzanai Ndambakuwa…·Brian J. Bacskai

This study shows anti-Aβ immunotherapy triggers rapid immune-vascular interactions in the leptomeningeal interface, leading to peripheral immune cell adhesion and potentially contributing to ARIA.

DOI 10.64898/2026.09.07.749938

mouseexperimental assay

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ImmunologybioRxivPreprintApr 16, 2026

Intranasal Anti-CD3 Antibody Treatment Attenuates Post-COVID Neuroinflammation and Enhances Hippocampal Neurogenesis and Cognitive Function in Mice

Peiwen Lu, Saef Izzy, Patrick da Silva…·Akiko Iwasaki

This study shows nasal anti-CD3 antibody treatment reduces neuroinflammation, enhances neurogenesis, and improves cognitive function in a mouse model of Long COVID.

DOI 10.64898/2026.04.07.716934

mouseproteomics

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ImmunologyNature CommunicationsPeer-reviewedApr 1, 2026

Th17 cells require the DNA repair sensor XPC to control oxidative DNA damage

Jefferson Antônio Leite, Natalia Notarberardino Bos, Luísa Menezes-Silva…·Niels Olsen Saraiva Câmara

This study identifies XPC as essential for protecting Th17 cells from oxidative DNA damage, showing its role in DNA repair, differentiation, and function.

DOI 10.1038/s41467-026-69914-y

mouseDNA methylation

𝕏 PostBluesky