Author

Luísa Menezes-Silva

Universidade de São PauloORCID 0000-0002-6860-6522Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Organism:human· 2 Assay:proteomics· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

Niels Olsen Saraiva CâmaraiD· 3 shared Anthony Gabry da SilveiraiD· 2 shared Bárbara Nunes PadovaniiD· 2 shared Jefferson Antônio LeiteiD· 2 shared José Arimatéa de Oliveira Nery NetoiD· 2 shared Laís Cavalieri ParedesiD· 2 shared Marcella CipelliiD· 2 shared Mariana Abrantes do AmaraliD· 2 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

Niels Olsen Saraiva CâmaraORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

HIF-1α integrates metabolic and immunoregulatory programs in RORγt⁺ regulatory T cells during intestinal inflammation

Marcella Cipelli, Eloisa M. da Silva, Luísa Menezes-Silva, Bárbara Nunes Padovani, Mariana Abrantes do Amaral, Laís Cavalieri Paredes, Bruno G. Nunes, Victor Yuji Yariwake, José Arimatéa de Oliveira Nery Neto, Natalia Notarberardino Bos, Anthony Gabry da Silveira, Joao Vinicius H. da Silva, Raquel de Souza Vieira, Suemy M. Yamada, Luís Felipe Serra Moreira, , Niels Olsen Saraiva Câmara

This study identifies HIF-1α as a regulator of metabolic and immunoregulatory programs in RORγt⁺ Tregs during intestinal inflammation, showing its role in maintaining suppressive function and limiting inflammation.

bioRxiv · Aug 19, 2026 · PreprintImmunology

Th17 cells require the DNA repair sensor XPC to control oxidative DNA damage

Jefferson Antônio Leite, Natalia Notarberardino Bos, Luísa Menezes-Silva, Eloísa Martins da Silva, Giovana da Silva Leandro, Guilherme Comparotto Moreira de Goes, Patrick da Silva, S. A. Oliveira, Eder Soares de Almeida Santos, Hedden Ranfley, Ilaria Palagi, Magaiver Andrade-Silva, Camila Pontes Ferreira, José Arimatéa de Oliveira Nery Neto, Victor Yuji Yariwake, , Niels Olsen Saraiva Câmara

This study identifies XPC as essential for protecting Th17 cells from oxidative DNA damage, showing its role in DNA repair, differentiation, and function.

Nature Communications · Apr 1, 2026Peer-reviewedImmunology

DRP1-mediated mitochondrial fission integrates growth hormone signaling with metabolic and stress adaptation in triple-negative breast cancer

Juliana Moreira Mendonça-Gomes, Mariana Tominaga Pereira, Luísa Menezes-Silva, Luis Eduardo Duarte Gonçalves, Mariana Abrantes do Amaral, Laís Cavalieri Paredes, Camila Morales Fenero, Bárbara Nunes Padovani, Mario Costa Cruz, Niels Olsen Saraiva Câmara

This study shows GH promotes TNBC progression through DRP1-mediated mitochondrial fission, linking metabolic reprogramming to cell-cycle progression and tumor microenvironment changes.

bioRxiv · Mar 10, 2026 · PreprintCancer Biology

Escherichia coli-induced gut IL-33 release inhibits lung type 2 allergic responses

Caio Loureiro Salgado, Marina Caçador Ayupe, Juliana Falcão Rodrigues, Leonardo Mandu Gonçalves, Luísa Menezes-Silva, Bárbara Cristina Pizzolante, Bernardo de Castro Oliveira, Guilherme William da Silva, Francielly Moreira, Érick Esteves de Oliveira, Marcelo Valdemir de Araújo, Gabriele Manamy Baba Rodrigues, Jofer Andree Zamame Ramirez, Kristen Brammer, Igor Santiago-Carvalho, , Denise Morais da Fonseca

This study shows that exposure to ETEC or its toxin LT reduces lung allergic inflammation by inhibiting IL-33 responses in ILC2 cells through a gut-derived negative feedback loop.

bioRxiv · Nov 7, 2025 · PreprintImmunology