Author

Keith J. August

Children's Mercy HospitalORCID 0000-0002-5690-0855Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:long-read sequencing· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Alan S. GamisiD· 2 shared Byunggil YooiD· 2 shared Erin M. GuestiD· 2 shared Irina PusheliD· 2 shared Lisa A. LansdoniD· 2 shared Margaret Gibson· 2 shared Midhat S. FarooqiiD· 2 shared Terrie G. FlattiD· 2 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Alan S. GamisORCID

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2 papers

Recent·Most cited

A comprehensive bulk and single-cell transcriptional atlas of pediatric leukemias

Irina Pushel, Tarun Karthik Kumar Mamidi, Byunggil Yoo, Lisa A. Lansdon, Daniel A. Louiselle, Margaret Gibson, Erin M. Guest, Nicole M. Wood, Keith J. August, Terrie G. Flatt, Alan S. Gamis, Tomi Pastinen, Midhat S. Farooqi

This study presents a comprehensive bulk and single-cell transcriptional dataset of 69 pediatric leukemia patients, demonstrating its utility in improving leukemia characterization and clinical testing.

bioRxiv · Dec 25, 2025 · PreprintCancer Biology

Successful classification of clinical pediatric leukemia genetic subtypes via structural variant detection using HiFi long-read sequencing

Lisa A. Lansdon, Byunggil Yoo, Ayşe Gökçe Keşküş, Irina Pushel, Chengpeng Bi, Tanveer Ahmad, Asher Bryant, Adam Walter, Margaret Gibson, Mary Rindler, Weijie Li, Sultan S. Habeebu, Linda D. Cooley, John C. Herriges, Elena A. Repnikova, , Midhat S. Farooqi

This study shows that HiFi long-read sequencing can detect clinically relevant structural variants in pediatric leukemia, improving subtype classification.

medRxiv · Nov 5, 2024 · PreprintGenetic & Genomic Medicine