Author

Douglas M. Anderson

University of Rochester MedicineORCID 0000-0002-5703-1743Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:gene regulatory network inference· 1 Assay:multiome· 1 Research Focus:perturbation response prediction· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Kelly M. Anderson· 2 shared Pornthida PoosalaiD· 2 shared Sean R. LindleyiD· 2 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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2 shared papersMolecular Biology

Kelly M. Anderson

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJul 26, 2019

Targeting Toxic Nuclear RNA Foci with CRISPR-Cas13 to Treat Myotonic Dystrophy

Pornthida Poosala, Sean R. Lindley, Kelly M. Anderson, Douglas M. Anderson

This paper demonstrates the use of CRISPR-Cas13 to target and manipulate toxic nuclear RNA foci in myotonic dystrophy type 1, offering tools for visualization and cleavage of CUG repeat RNA.

4 citations

humanexperimental assay

𝕏 PostBluesky

Molecular BiologybioRxivPreprintJan 26, 2019

Targeted Cleavage and Polyadenylation of RNA by CRISPR-Cas13

Kelly M. Anderson, Pornthida Poosala, Sean R. Lindley, Douglas M. Anderson

This paper demonstrates a method to achieve site-specific RNA cleavage and polyadenylation using CRISPR-Cas13 fused to NUDT21, named Postscriptr, for non-genomic gene expression manipulation.

15 citations

humanmultiome

𝕏 PostBluesky