Author

Michael Zahn

Medizinische Hochschule HannoverORCID 0000-0002-5709-8665Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Research Focus:host-pathogen & immune response· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrew R. PickfordiD· 1 shared Bruce R. LichtensteiniD· 1 shared Daniel J. HincheniD· 1 shared Elaine M. RudgeiD· 1 shared J.E. McGeehaniD· 1 shared Kerry R. GreeniD· 1 shared Liliana OliveiraiD· 1 shared Lindsay D. EltisiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Andrew R. PickfordORCID

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2 papers

Recent·Most cited

Engineering a cytochrome P450 O-demethylase for the bioconversion of hardwood lignin

Megan E Wolf, Daniel J. Hinchen, Michael Zahn, J.E. McGeehan, Lindsay D. Eltis

This study characterizes a cytochrome P450 enzyme involved in lignin degradation and engineers it to catalyze both 4-alkylguaiacol and 4-alkylsyringol O-demethylation, enhancing its utility in biocatalytic lignin valorization.

ACS Synthetic Biology · Jul 6, 2026Peer-reviewedBiochemistry

Engineering surface electrostatics affords control over morphological preference, synergy, and activity in polymer degrading enzymes

Liliana Oliveira, Elaine M. Rudge, Michael Zahn, Victoria L. Bemmer, Kerry R. Green, Andrew R. Pickford, Bruce R. Lichtenstein

This study redesigns the surface charge of a PET-hydrolase to enhance its activity and morphological preference, revealing synergistic interactions with the wildtype enzyme.

bioRxiv · Jan 6, 2025 · PreprintBiochemistry