Bruce R. Lichtenstein

This paper designs de novo flavoproteins with controlled excited state dynamics using computational methods and experimental validation.

This paper designs redox proteins with tunable electron transfer properties by replacing heme B with non-natural metalloporphyrins, achieving redox potential modulation of over 400 mV.

This study redesigns the surface charge of a PET-hydrolase to enhance its activity and morphological preference, revealing synergistic interactions with the wildtype enzyme.