Author

Marcelo Pérez-Pepe

Yale Cancer CenterORCID 0000-0002-5712-0973Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:metagenomics· 2 Approach:statistical model· 2 Assay:proteomics· 1

Frequent Co-Authors

Claudio R. AlarcóniD· 2 shared Hengyi LiiD· 2 shared Yansheng LiuiD· 2 shared Alexander NguyeniD· 1 shared Anthony W. DesotelliD· 1 shared Azime Akçaöz-AlasariD· 1 shared Bing HaniD· 1 shared Bünyamin AkgüliD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMolecular Biology

Claudio R. AlarcónORCID

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2 papers

Recent·Most cited

Molecular BiologyMolecular CellPeer-reviewedJul 31, 2026

METTL3 promotes cell cycle progression via activation of transcriptional elongation.

Azime Akçaöz-Alasar, Yanhua Wang, Hang Li…·Claudio R. Alarcón

The paper shows that METTL3 phosphorylation by CDK1 promotes transcriptional elongation and cell cycle progression through the m6A/7SK/P-TEFb axis.

DOI 10.1016/j.molcel.2026.07.011

humanmetagenomics

𝕏 PostBluesky

Molecular BiologybioRxivPreprintOct 17, 2022

7SK methylation Promotes Transcriptional Activity

Marcelo Pérez-Pepe, Anthony W. Desotell, Hengyi Li…·Claudio R. Alarcón

The paper shows that m6A methylation of 7SK RNA promotes transcriptional activity in response to growth factor stimulation by releasing the HEXIM1/P-TEFb complex.

DOI 10.1101/2022.10.17.512631

humanmetagenomics

𝕏 PostBluesky