Thomas M. Pearce

This study identifies AHCY as a key driver of epigenetic and metabolic reprogramming in ZFTA-RELA ependymomas, revealing its role in promoting tumor growth through pyrimidine synthesis and asparagine dependency.

This study evaluates how well frozen pathology foundation models transfer to cancer-related H&E and neurodegenerative IHC tasks, finding better performance on H&E tasks than on specialized IHC tasks.

This paper develops a deep learning framework to segment and quantify cerebral amyloid angiopathy in whole-slide histopathology images, achieving high accuracy and robust generalization across cohorts.

The paper compares movement-related neuronal activity in cerebellar- and basal ganglia-recipient regions of the macaque thalamus, finding distinct temporal and directional encoding patterns.