Author

Kulandaimanuvel Antony Michealraj

University of PittsburghORCID 0000-0002-3967-0816Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Approach:statistical model· 1

Frequent Co-Authors

Aaron Y. MochizukiiD· 1 shared Alberto DelaidelliiD· 1 shared Aleena K. S. ArakakiiD· 1 shared Andrew M. DonsoniD· 1 shared Antonio C.T. Cobos· 1 shared Baoli HuiD· 1 shared Bhagyalakshmi Manikandan· 1 shared Bokai ZhuiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

Aaron Y. MochizukiORCID

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2 papers

Recent·Most cited

Adenosylhomocysteinase drives epigenetic and metabolic reprogramming in ZFTA-RELA ependymoma

Navneesh Yadav, Olivia Pelcher, Raja Gopal Reddy Mooli, Robert B Cameron, Alberto Delaidelli, Kannan Boosi Narayana Rao, Bhagyalakshmi Manikandan, Senna Visser, Antonio C.T. Cobos, Vishal Parmar, Yuvraj Kayola, Siva Kumar Natarajan, Yash Patel, Jiao Zhang, Hardik Shah, , Kulandaimanuvel Antony Michealraj

This study identifies AHCY as a key driver of epigenetic and metabolic reprogramming in ZFTA-RELA ependymomas, revealing its role in promoting tumor growth through pyrimidine synthesis and asparagine dependency.

bioRxiv · Oct 7, 2026 · PreprintCancer Biology

A Systems approach identifies MERTK as a therapeutic vulnerability in ZFTA-RELA-driven ependymomas

Marina Chan, Songli Zhu, Zachary R. Russell, Sonali Arora, Aleena K. S. Arakaki, Joel Markus Vaz, Deby Kumasaka, Frank Szulzewsky, Kulandaimanuvel Antony Michealraj, Eric C. Holland, Taranjit S. Gujral

This study identifies MERTK as a therapeutic target in ZFTA-RELA-driven ependymomas through transcriptomic analysis and drug screening.

Proceedings of the National Academy of Sciences · Feb 10, 2026Peer-reviewedCancer Biology