Laurence Faucher‐Giguère

The paper shows that SNORA81-guided pseudouridylation at a specific 28S rRNA site influences selective translation and ovarian cancer cell proliferation.

This study identifies a ribosomal RNA modification regulated by SNORA81 that affects translation of PI3K/AKT activators in high-grade serous ovarian carcinoma.

This study benchmarks nanopore direct RNA sequencing for pseudouridine quantification in human ribosomal RNA, showing high accuracy and reproducibility across multiple cell types.

snoFlake identifies snoRNA-RBP complexes and reveals SNORD22 as a splicing regulator by interacting with U5 snRNP components.

SnoBIRD identifies and refines C/D box snoRNA annotations across eukaryotes by distinguishing expressed snoRNAs from pseudogenes.