Virginie Marchand

The paper shows that SNORA81-guided pseudouridylation at a specific 28S rRNA site influences selective translation and ovarian cancer cell proliferation.

This study shows that 2'-O-Me modifications on rRNA are dynamically regulated during seed-to-seedling transition in Arabidopsis and affect ribosome translation.

This study identifies two sRNAs in Staphylococcus aureus that regulate zinc homeostasis, showing their role in Zn-sparing responses and adaptation to metal limitation.

This study benchmarks nanopore direct RNA sequencing for pseudouridine quantification in human ribosomal RNA, showing high accuracy and reproducibility across multiple cell types.

This study identifies Rlig1 as a regulator of ribosome function and translation under oxidative stress by showing its interaction with ribosomal proteins and its role in maintaining translational activity.

The paper shows that specific snoRNAs pseudouridylate rRNA, affecting ribosome function, lipid metabolism, and neurodegeneration in Drosophila.

This study maps tRNA modifications in Streptococcus mutans and S. pneumoniae, revealing shared losses and clade-specific adaptations in modification genes and metabolic strategies.

ViREn is a two-step method that purifies dengue virus RNA with high purity, revealing a 5-methylcytosine modification mediated by NSUN6 that affects RNA turnover.

The paper identifies rRNA methylation dynamics as a mechanism regulating translation efficiency and HSC fitness during hematopoietic differentiation.

This paper maps tRNA modifications in Vibrio cholerae using chemical sequencing and gene deletions, revealing species-specific features and their role in translation and stress responses.

This study investigates the RPL5-I60V mutation in T-ALL, showing it increases translation and alters drug sensitivity in leukemia cells.

The paper provides a comprehensive analysis of tRNA modifications in Staphylococcus aureus, revealing species-specific features and decoding dynamics.

The paper identifies additional tRNA targets of the AriB nuclease in the PARIS system and shows that phage-encoded tRNAs can inhibit this defense.

The paper identifies a bifunctional snoRNA, snR107, that guides rRNA modification and scaffolds gametogenesis effectors in fission yeast.

This study shows that Fibrillarin regulates oncogenic protein pools and ribosomal composition in triple-negative breast cancer by modulating rRNA methylation and RPS28 levels.

The paper investigates how 2'-O-methylation of rRNA affects ribosome function in Saccharomyces cerevisiae, showing its role in cell growth and antibiotic sensitivity.

The paper maps tRNA modifications and their synthesis genes in two Bartonella species, identifying gene reductions linked to reductive evolution.

This study maps 2'-O-methylation sites and identifies C/D box snoRNAs in Drosophila rRNAs, showing limited stress-induced variation in methylation levels.

This study shows FUS regulates snoRNA expression, affecting rRNA modifications like 2-O-Me and pseudouridylation, which may contribute to ALS pathology.

The paper identifies a novel FTSJ1 pathogenic variant and shows its role in neuron morphology and learning performance through RiboMethSeq and transcriptome analysis in human and Drosophila models.

This study investigates the role of fibrillarin in ribosome biogenesis and its impact on neural crest cell development in Xenopus laevis, revealing developmental defects and hypomethylation patterns in rRNA.

This study identifies two tRNA methyltransferases in Drosophila that modulate small RNA silencing and lifespan by modifying specific tRNAs.