This study evaluates the NeoLNP RNA Transfection Kit, identifying optimal parameters for transfection efficiency and providing practical guidelines for RNA delivery.

DOI 10.1016/j.ymeth.2025.05.007

experimental assay

GenomicsBiomarker ResearchPeer-reviewedJan 7, 2024

Long-read Transcriptome Landscapes of Primary and Metastatic Liver Cancers at Transcript Resolution

Zhiao Chen, Qili Shi, Yiming Zhao…·Xianghuo He

The paper defines the full-length transcriptome of primary and metastatic liver cancers and identifies isoform-level diversity and metastasis-specific transcripts with clinical implications.

9 citations

humanlong-read sequencing

GeneticsbioRxivPreprintSep 3, 2020

The genetic sequences prone to copy number variation and single nucleotide polymorphism are linked to the repair of the poisoned DNA topoisomerase II

Chuo Jiang, Cong Ma, Detao Wang…·Jiaxi Wu

The paper identifies DNA sequences associated with TOP2 poisoning that are linked to genetic variations contributing to multiple diseases.

DOI 10.1101/2020.09.03.280669

humanDNA methylation

GeneticsbioRxivPreprintAug 17, 2020

In-depth analysis reveals complex molecular etiology of idiopathic cerebral palsy

Na Li, Pei Zhou, Hongmei Tang…·Hao Hu

This study identifies molecular risk factors and mechanisms in idiopathic cerebral palsy through clinical and molecular analysis of 120 families.

4 citations

humanbulk RNA-seq