Hanna Kokko

Stochastic failure accumulation as a foundation for exponential mortality and selective disappearance

The paper develops a mathematical framework for demographic senescence, showing how interdependent sub-systems lead to faster senescence and Gompertz-Makeham mortality patterns.

Competition among kin generates balancing selection in a wild population

Heritable variation is maintained due to resource competition being more intense among kin.

Beyond abstract selection coefficients: Protandry impacts the buildup of heterozygote advantage over the lifespan in a color polymorphic moth

The paper models how protandry affects polymorphism maintenance in a moth by considering the timing of mortality and reproduction, showing its impact on heterozygote advantage.

A century of theories of balancing selection

This paper reviews the development of balancing selection theory over the last century and examines its biological scenarios and genetic system features.

Infection dynamics of endosymbionts that manipulate arthropod reproduction

This paper models infection dynamics of endosymbionts manipulating arthropod reproduction, showing that invasion success depends on both manipulation type and priority effects.

Sex-specific immunocompetence: resistance and tolerance can both be futile but not under the same circumstances

The paper models optimal immunity investment under varying parasite pressure and sexual selection, showing resistance futility at high parasite abundance and tolerance futility at high virulence, but joint resistance-tolerance traits remain profitable.

Mitigating Mitochondrial Genome Erosion Without Recombination

The paper models how mitochondrial genomes avoid mutational erosion through uniparental inheritance and fusion-fission cycles, showing that recombination is not necessary for this process.