Structure and functional implications of WYL-domain-containing transcription factor PafBC involved in the mycobacterial DNA damage response
Andreas U. Müller, Marc Leibundgut, Nenad Ban, Eilika U. Weber-Ban
The paper determines the crystal structure of PafBC, a mycobacterial transcription factor with a WYL domain, and suggests RNA binding activates it through structural analysis and mutational screening.
Nature Communications · Oct 11, 2019Peer-reviewedMolecular Biology