Author

Heather N. Zook

City Of Hope National Medical CenterORCID 0000-0002-5780-2042Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

Hsun Teresa KuiD· 3 shared Hirotake KomatsuiD· 2 shared Hiroyuki KatoiD· 2 shared Angela S. BakeriD· 1 shared Behnam BadieiD· 1 shared Blake BrewsteriD· 1 shared Ching OuyangiD· 1 shared Christine E. BrowniD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersCell Biology

Hsun Teresa KuORCID

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintOct 20, 2026

Distinct viability and oxygen-sensing responses to hypoxia and reoxygenation in pancreatic islets

Hiroyuki Kato, Heather N. Zook, Neslihan Erdem…·Hirotake Komatsu

This study examines how pancreatic islets respond to different oxygen levels and reoxygenation, finding that viability decreases under hypoxia but is preserved at 5% and 18% O2, with reoxygenation not fully restoring viability.

DOI 10.64898/2026.10.18.759980

ratbulk RNA-seq

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BioengineeringbioRxivPreprintOct 15, 2026

Oxygen-permeable microwell plates for high-throughput spheroid culture

Jun Takahashi, Hiroyuki Kato, Heather N. Zook…·Hirotake Komatsu

This paper develops oxygen-permeable microwell plates using PMP to improve spheroid culture by enhancing oxygenation and reducing hypoxia.

DOI 10.64898/2026.10.05.756623

experimental assay

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Cancer BiologybioRxivPreprintOct 6, 2026

A long-term organotypic slice culture model of patient high-grade glioma preserving tumor heterogeneity and architecture, and specificity of CAR T cell targeting

Simiao Wang, Ching Ouyang, Heather N. Zook…·Michael E. Barish

DOI 10.64898/2026.10.04.756617

humanbulk RNA-seq

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