Author

Michael E. Barish

City Of Hope National Medical CenterORCID 0000-0003-3011-4861Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Neuroscience· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:differential expression· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Research Focus:benchmarking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Christine E. BrowniD· 4 shared Blake BrewsteriD· 2 shared Margarita GutovaiD· 2 shared Russell C. RockneiD· 2 shared Albert G. TsaiiD· 1 shared Alejandra Velazquez Ojeda· 1 shared Alex KongiD· 1 shared Angela S. BakeriD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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4 shared papersCancer Biology

Christine E. BrownORCID

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4 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 6, 2026

A long-term organotypic slice culture model of patient high-grade glioma preserving tumor heterogeneity and architecture, and specificity of CAR T cell targeting

Simiao Wang, Ching Ouyang, Heather N. Zook…·Michael E. Barish

DOI 10.64898/2026.10.04.756617

humanbulk RNA-seq

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Cancer BiologyCancer CellPeer-reviewedDec 11, 2025

Multi-omic landscape of human gliomas from diagnosis to treatment and recurrence

Hadeesha Piyadasa, Benjamin Oberlton, Mikaela K. Ribi…·Michael Angelo

This study analyzes multi-omic data from gliomas to identify therapeutic escape mechanisms and TME evolution, finding that N-glycosylation classifies tumor grade and immune transcriptome predicts GBM survival.

41 citationstop 1%

humanspatial transcriptomics

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Systems BiologybioRxivPreprintJun 4, 2025

Study of combination CAR T-cell treatment for glioblastoma using mathematical modeling

Runpeng Li, Michael E. Barish, Margarita Gutova…·Heyrim Cho

This study uses a mathematical model to explore combination CAR T-cell treatments for glioblastoma, showing that early intervention and spatially targeted delivery are effective strategies.

DOI 10.1101/2025.06.04.657886

humanstatistical model

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NeurosciencebioRxivPreprintFeb 12, 2025

Modeling cerebral development in vitro with L-MYC-immortalized human neural stem cell-derived organoids

Alejandra Velazquez Ojeda, Dina Awabdeh, Blake Brewster…·Michael E. Barish

This paper presents an organoid-based platform using L-MYC-immortalized human neural stem cells to model cerebral development in vitro, showing similar gene expression patterns to normal cortical development.

2 citations

humanbulk RNA-seq

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